FAQ

Frequently Asked Questions

Everything you need to know about the Kyra Gupta Research Grant and Kyra's Hope Fellowship.

General

About the Program

The Kyra Gupta Research Grant funds pediatric cancer research through direct financial grants and technology talent (engineering teams provided through the Kyra’s Hope Fellowship). We support labs with capital, computational expertise, or both.

This program is run by Kyra’s Hope Foundation, a 501(c)(3) nonprofit organization (EIN: 41-2583689). Learn more at kyrashope.org.

Childhood cancer receives only 4% of federal research funding. Only 8 drugs have been approved for pediatric cancer in 45 years. There is a typical $10M translational gap between academic discovery and clinical trials where most breakthroughs stall. We exist to help close that gap.

Yes. Kyra’s Hope Foundation is a registered 501(c)(3), holds Candid’s Platinum Seal of Transparency, and partners with accredited research institutions. All operations are transparent and publicly documented.

Our Approach

Strategy & Credibility

Scientific credibility is foundational to how we operate. We do not generate or direct the science ourselves, we support work led by experienced researchers and institutions. Projects are selected based on scientific rigor, translational potential, and the urgency of unmet need. We collaborate with established organizations that have built strong scientific advisory boards and research evaluation processes, allowing us to identify high-quality research with greater confidence.

Rare pediatric cancers like Ewing sarcoma receive less than 1% of already-tiny pediatric cancer funding. The metastatic survival rate for Ewing sarcoma is under 20% and has been unchanged for decades. Commercial pharma bypasses these diseases because ~600 cases per year doesn’t generate ROI, it’s a market failure that only philanthropy can fix. We focus where the gap is most acute and where progress has been slowest.

Those are large, established organizations doing critical work, and we deeply respect them. We complement rather than compete with them by focusing on a specific gap they’re not structured to address: helping research move faster through embedded engineering and AI expertise. Most foundations fund research; we do too, but our core difference is integrating technical talent directly into research teams in rare childhood cancers like Ewing sarcoma, where progress has been slow and support is limited.

Your funding is directed toward both advancing research and accelerating how it progresses. A portion supports targeted research grants in underfunded childhood cancers. The rest enables us to embed technical expertise, engineering and AI, directly into research teams to reduce bottlenecks and help work move faster. We also invest in building reusable tools and systems so impact extends beyond individual projects. Each dollar supports research and makes that research more efficient.

We are building a structured model designed for long-term scalability. Our technical work is not informal volunteering, it is organized through defined roles, time-bound commitments, and project-based delivery, which ensures accountability and continuity. As we grow, we plan to transition critical functions into funded roles where needed. We also build reusable tools and systems so each project creates value beyond a single engagement. The combination of structure, talent, and reusable infrastructure allows the model to scale sustainably.

For Researchers

Research Grant Questions

Direct research funding, technology talent (a dedicated engineering team through our Kyra’s Hope Fellowship), or a combination of both, tailored to your lab’s needs.

A team of 3–5 engineers plus a senior Tech Lead for 6 months, delivering 520–780 hours of engineering work. This includes software development, data science, ML model building, and more.

Expression of Interest → Technical Discovery Call → Project Scoping → MOU & Grant Award → Team Assignment & Kickoff. The full process takes approximately 4–6 weeks.

Funding: pilot studies, translational research, reagent costs. Tech talent: genomic data pipelines, ML classification models, drug screening analysis, data visualization dashboards, image analysis tools.

IP ownership is determined case-by-case and defined in the Memorandum of Understanding (MOU). The default is institutional ownership.

For technology talent grants, volunteers only work with de-identified data. No patient data is ever shared. All data handling follows institutional guidelines.

No. Both funding and technology talent are provided at no cost to the lab.

Designate a point of contact, engage with the foundation regularly, and acknowledge the foundation and fellows in resulting publications.

For Volunteers

Fellowship Questions

5 hours per week for 6 months. The program is cohort-based with defined start and end dates, not rolling admission.

No. This is a volunteer fellowship. The value is in the credential, co-authorship on publications, real-world portfolio, letters of recommendation, research network, and meaningful impact.

2+ years of technical experience in software engineering, data science, ML, or related fields. Bioinformatics experience is valuable but not required, we’ll teach you the domain.

The foundation matches fellows to projects based on skills, experience, and project needs. We consider your interests when making assignments.

Yes. Fellows making substantive contributions receive co-authorship on resulting research papers, following ICMJE guidelines.

Give 2 weeks notice. Teams are designed with redundancy (4–5 people) so they can absorb departures.

A cohort-wide event where all teams present their results to researchers, foundation leadership, and guests. It’s a celebration of impact and excellent for your portfolio.

Still have questions? Email us at research@kyrashope.org.